Open Projects
Sea4Pain
Share article

https://goparity.com/projects/sea4pain-500

Sea4Pain

Portuguese non-opioid for chronic pain
Investment overview
Impact category
social_economy
Investment type
loan
Yearly interest
8
%
Term
6
months
Risk level
The Risk Rating is the result of our credit risk assessment, which looks at the promoter’s financial strength and the project’s viability. It’s shown from A+ (lowest risk) to D (highest risk) and helps you compare projects and make informed decisions.
A
D
C
Invest now
Join 2881 investors making an impact
Share article

https://goparity.com/projects/sea4pain-500

Description
Impact
Financial viability

Ready to explore this investment opportunity?

Create an account or log in to view the full project details and invest.

Get started

Already have an account?

Log in
Promoter

What will you be financing?

Sea4Us is a biotechnology company dedicated to transform marine-inspired compounds into innovative therapies for unmet medical needs.

Sea4Us leverages the unique chemical compounds found in marine organisms to develop innovative treatments for chronic pain. Marine resources, such as sea sponges, provide a diverse array of bioactive molecules with the potential to target pain pathways. In the framework of its ‘Sea4Pain’ project, Sea4Us is transforming these marine-inspired compounds into optimised and synthesisable pharmaceutical ingredients. 

To take the development of Sea4Pain through to the first human trials and its licensing and marketing to the pharmaceutical industry, Sea4Us has launched Sea4Market, approved under the European Innovation Council's (EIC) Accelerator programme, representing a total investment of 5.9 million euros.

The funds raised through this campaign will be used to advance the second payment of the EIC Accelerator grant. The project will strengthen Sea4Us' operational capabilities and its readiness to obtain license agreements with pharmaceutical companies on a global level. 

Sea4Pain is a non-opiate analgesic for the treatment of moderate-severe chronic pain. This analgesic acts through a new mechanism of action, which allows for analgesic efficacy equivalent to opiates, but without altering sensory perception, without affecting the brain, and without the unwanted side effects of opiates. This drug, derived and refined from a molecule found in a marine sponge from the Portuguese cost, in Sagres, has proven its efficacy in cellular models and 6 different chronic disease models. The safety observed in the treatment makes it possible to offer a safe and effective alternative to existing pain treatments without the risk of addiction or habituation. This technology has been patented by Sea4Us in key international market regions.

The project will run for three years, starting on 1 March 2024 and ending on 28 February 2027. The main goal is to advance the development of Sea4Us' innovative medicines, particularly Sea4Pain, by financing key R&D activities such as regulated pre-clinical toxicology, clinical trial applications and the execution of first-in-human clinical trials. The project also has the support of the EIC-Fund to accelerate the commercialisation of the drug. 

You can learn more here: Sea4Us_Sea4Pain_.pdf

What is the impact?

Direct

Contribution to health through research and development of innovative treatments: with the funding, Sea4Us will continue the development of innovative treatments for chronic pain based on marine compounds. Based on research and development processes, the promoter has created a therapeutic drug from molecules found in a marine sponge, with high efficacy and no serious side effects. The promoter focuses on efficient production and development processes that allow for lower material losses and lower production costs, with the aim of keeping costs low and providing a product that is more accessible to patients.

Creation and maintenance of skilled jobs: the implementation phase to be funded by this campaign will result in one person being hired. Sea4Us, which currently has a team of 19 people, contributes to the creation of highly qualified jobs in the Algarve region of Portugal, with 18 highly qualified people, 10 of whom are PhDs.

Indirect

Promoting the quality of life of patients with chronic pain: through treatment with Sea4Pain, patients will be able to access an effective analgesic medication that reduces pain without adverse side effects and without the potential for addiction, representing an important and necessary alternative to the use of opioids. The non-opioid drugs in this solution provide pain relief and contribute to improving patients' quality of life. The commercialization of Sea4Pain will allow Sea4Us to reinvest in its production, developing new drugs for other pressing clinical needs, and delivering treatments that impact people's lives.

Contribution to the maintenance of marine ecosystems and sustainable marine economic activities: the promoter's central purpose is the protection and maintenance of marine resources, carrying out ecosystem monitoring, recording and managing invasive species, and contributing to the repopulation of native species. Sea4Us is a voluntary signatory of the UN Global Compact, a member of the European Animal Research Association and prioritizes transparency and ethics in its processes.

Promoting the economic and scientific development of the Algarve and Portugal: Sea4Us has its laboratory in Sagres, in the Algarve, where biotechnology activities are carried out, mobilizing a network of dozens of active partners to implement projects and disseminate knowledge in this region of Portugal. In this way, it is possible to raise the potential of the country's marine resources and the development of differentiating activities in the blue economy to an international scale, contributing to local economic development. In addition, through partnerships with universities, it contributes to the advancement of scientific knowledge, having collaborated on seven master's theses already completed at the company, two doctoral theses completed and another five in progress.

Impact indicators

CO2 avoided per year
clean energy
1
created by our projects
of sustainable
impacted

Contribution to the Sustainable Development Goals

About the Promoter

About Adega Cooperativa Cantanhede

Direct

Contribution to health through research and development of innovative treatments: with the funding, Sea4Us will continue the development of innovative treatments for chronic pain based on marine compounds. Based on research and development processes, the promoter has created a therapeutic drug from molecules found in a marine sponge, with high efficacy and no serious side effects. The promoter focuses on efficient production and development processes that allow for lower material losses and lower production costs, with the aim of keeping costs low and providing a product that is more accessible to patients.

Creation and maintenance of skilled jobs: the implementation phase to be funded by this campaign will result in one person being hired. Sea4Us, which currently has a team of 19 people, contributes to the creation of highly qualified jobs in the Algarve region of Portugal, with 18 highly qualified people, 10 of whom are PhDs.

Indirect

Promoting the quality of life of patients with chronic pain: through treatment with Sea4Pain, patients will be able to access an effective analgesic medication that reduces pain without adverse side effects and without the potential for addiction, representing an important and necessary alternative to the use of opioids. The non-opioid drugs in this solution provide pain relief and contribute to improving patients' quality of life. The commercialization of Sea4Pain will allow Sea4Us to reinvest in its production, developing new drugs for other pressing clinical needs, and delivering treatments that impact people's lives.

Contribution to the maintenance of marine ecosystems and sustainable marine economic activities: the promoter's central purpose is the protection and maintenance of marine resources, carrying out ecosystem monitoring, recording and managing invasive species, and contributing to the repopulation of native species. Sea4Us is a voluntary signatory of the UN Global Compact, a member of the European Animal Research Association and prioritizes transparency and ethics in its processes.

Promoting the economic and scientific development of the Algarve and Portugal: Sea4Us has its laboratory in Sagres, in the Algarve, where biotechnology activities are carried out, mobilizing a network of dozens of active partners to implement projects and disseminate knowledge in this region of Portugal. In this way, it is possible to raise the potential of the country's marine resources and the development of differentiating activities in the blue economy to an international scale, contributing to local economic development. In addition, through partnerships with universities, it contributes to the advancement of scientific knowledge, having collaborated on seven master's theses already completed at the company, two doctoral theses completed and another five in progress.

Promoter website

https://sea4us.pt/en/

Team

[{"id":310,"promoter_id":344,"name":"Pedro A. Lima","description":"","link":"https://www.linkedin.com/in/pedro-afonso-lima/","role":"Co-founder, President of Board of Directors and CEO","member_photo":"https://991934249232-prod-octobercms-public-storage.s3.eu-west-1.amazonaws.com/public/679/a18/873/679a188733168323511513.jpeg","avatar_id":178627},{"id":311,"promoter_id":344,"name":"Nuno Leitão","description":"","link":"https://www.linkedin.com/in/nuno-leitao-01a37a17/","role":"Co-founder, Member of the Board of Directors, and CFO","member_photo":"https://991934249232-prod-octobercms-public-storage.s3.eu-west-1.amazonaws.com/public/679/a19/b73/679a19b73d084360491574.jpeg","avatar_id":178628},{"id":312,"promoter_id":344,"name":"Tânia Ferreira","description":"","link":"https://www.linkedin.com/in/tania-catarina-ferreira/","role":"COO, Business Development & Innovation","member_photo":"https://991934249232-prod-octobercms-public-storage.s3.eu-west-1.amazonaws.com/public/679/a1a/346/679a1a346f498712141569.jpeg","avatar_id":178629},{"id":313,"promoter_id":344,"name":"André Bastos","description":"","link":"https://www.linkedin.com/in/andr%C3%A9bastos/","role":"Co-founder, Member of the Board of Directors and CTO","member_photo":"https://991934249232-prod-octobercms-public-storage.s3.eu-west-1.amazonaws.com/public/679/a50/11b/679a5011bcbcb142661007.jpeg","avatar_id":178646}]

Business Model

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Suspendisse varius enim in eros elementum tristique. Duis cursus, mi quis viverra ornare, eros dolor interdum nulla, ut commodo diam libero vitae erat. Aenean faucibus nibh et justo cursus id rutrum lorem imperdiet. Nunc ut sem vitae risus tristique posuere.

Sign up to access the full details

Open account
Already have an account? Sign in
Project progress

0%

New opportunity. Be among the first to invest.
of full round

64000000

minimum

80000000

target

80000000

maximum

Closed

Project progress
Sagres
Simulate your investment

Estimate returns and repayment schedule.

Discover other open projects you may like

See all projects

Great investments from people just like you

Goparity allowed me to dive into the investment world in a responsible and conscious way. With an incredible support team, I invested in project with meaning and impact!

Smiling woman with curly hair wearing a light pink top against a plain background.

Natacha Lemos Van Doorn

Investor since 2019

Five vertical yellow bars of different heights arranged in a wave-like pattern on black background.

It’s great to be part of Goparity’s family! Costumer Support treats me like I’m one of them, plus its business model allows me to support sustainable and eco-friendly projects. What more cloud I ask for? :)

Close-up of smiling person wearing sunglasses and a blue cap outdoors in sunlight.

Catarina Sousa

Investor since 2023

Icon of three stacked blue-grey square layers with rounded corners and white borders.

Economic development and ecological preservation shouldn’t have their back turned on each other, we should face the future with the opposite perspective if we want a future at all! Goparity allows that.

Smiling young man with short dark hair and beard wearing a grey checked shirt against a light background.

Pedro Pereira da Silva

Investor since 2019

A good option for those who like to invest in crowdfunding. Moreover knowingly it supports a more eco-friendly Portugal.

Smiling person wearing glasses and scarf standing inside a store with colorful shoes on shelves.

Tiago Almeida

Investor since 2020

Five vertical bars of varying heights arranged to form a symmetrical wave pattern.

Goparity has great Customer Support and makes me want to be friends with all the people behind the scenes who are so focused on creating a positive impact in the world.

Close-up portrait of a woman with light hair wearing a white knitted hat smiling gently.

Susanne Haefeli-Hestvik

Investor since 2017

Icon of three stacked green layers representing a stack or layers concept.

Joining Goparity was very simple and fast. One can see that there is a good team behind the scenes!

Black and white portrait of a man with curly hair and a mustache, arms crossed, wearing a dark shirt.

Hugo Ferreira

Investor since 2020

Auto-invest

Set your strategy once, grow it every month

Turn occasional investments into a disciplined, diversified strategy. Set your preferences, and Auto-Investment will match opportunities automatically — so your money work while life gets busy.

Investment strategy app screen with risk rating, auto investment info, and photos of solar panels and a boat crane.

Need financing?

Get an instant simulation and
receive an offer within 48 hours.

7.72% Portfolio IRR with stack icon, 60,000 Goparity users with user icon, large G logo on yellow background.

Download the app

Track projects, manage investments, and follow your returns.

Smartphone screen showing investing app with project progress and people impacted stats.